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This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of rat IL-2. The Rat IL-2 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Interleukin 2 (IL-2) is a 15 kDa glycoprotein encoded by a single gene located in the q26-28 region of human chromosome 4. It is a type of cytokine signaling molecule in the immune system, regulating the activities of white blood cells (leukocytes, often lymphocytes) responsible for immunity. IL-2 is part of the body’s natural response to microbial infection, and in discriminating between foreign (“non-self”) and “self”. IL-2 mediates its effects by binding to IL-2 receptors, a complex consisting of three chains, termed α (CD25), β (CD122) and γ (CD132).
Monitoring of IL-2 levels in serum provides more detailed insights in several pathological situations such as cancer, infectious diseases, transplant rejection, multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus and type I diabetes.
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